CLINICAL RESEARCH AT TIA

Building the evidence for a new era of women’s health

Some of the biggest opportunities in women’s health aren't just about discovering new science. They're about connecting what we already know, discovering what fragmented datasets have prevented us from seeing, and getting those insights into the hands of clinicians and patients.

Tia is building a clinical research platform designed to do all three.

Through longitudinal clinical care, research partnerships and new sources of health data, we're working to better understand how women's health evolves across a lifetime—and translate those insights into better preventive care.

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Women's health is connected. Our research should be too.

Healthcare often treats these as separate chapters of a woman's life. Increasingly, research tells us they aren't.

A pregnancy complication can reveal cardiovascular risk decades before heart disease appears. PMOS (PCOS) can be an early signal of lifelong cardiometabolic risk. Changes during perimenopause can provide important information about a woman's future cardiovascular and brain health.

Yet the data that could help us understand these relationships is fragmented across specialties, health systems, research studies—and increasingly, consumer health technologies.

Tia's research strategy starts by putting the woman back together.

Our integrated model of primary care, gynecology, mental health and specialty care gives us a longitudinal view of women's health across life stages and conditions. Through research partnerships, we can expand that picture further—bringing together clinical, laboratory, patient-reported and, with patient permission, wearable and other novel data.

From more data to better care

More health data isn't useful on its own.

The opportunity is to use richer, longitudinal datasets and new analytical approaches to ask better questions:

Which early signals predict disease years or decades later?
Which biomarkers matter for which women?
How do reproductive events alter a woman's long-term health trajectory?
Why do diseases progress differently across different populations?
Which interventions change those trajectories?
How can we identify risk—and intervene—earlier?

The ultimate goal isn't simply better prediction. It's better prevention.

Closing the translational research gap

There is another problem we believe is just as important.

Over the last decade, researchers have generated important new insights into women's cardiovascular, metabolic, reproductive, autoimmune and brain health. Too often, those insights take years to meaningfully change everyday care.

Tia is designed to help close that gap.

Because research and care live within the same clinical ecosystem, we can work with researchers and partners to:

Translate emerging evidence into women-specific clinical protocols
Test those protocols in real-world care
Learn how they perform across different populations
Give clinicians useful insights at the point of care
Continuously improve care based on what we learn

Research shouldn't end with publication. It should change how women are cared for.

A longitudinal view of women's health

Depending on the research question, study design and applicable patient consent and permissions, Tia research can incorporate data spanning:

Menstrual, reproductive and menopausal health
Fertility, pregnancy and postpartum history
Cardiovascular and metabolic health
Hormonal and other laboratory data
Mental health and patient-reported symptoms
Autoimmune and chronic conditions
Medications, interventions and treatment response
Lifestyle, behavioral and wearable data
Clinical care patterns and longitudinal health outcomes

Studying these signals together—and over time—creates the opportunity to see relationships that fragmented healthcare datasets can miss.

What we're studying

Reproductive aging + menopause

Understanding the menopause transition not as an isolated life stage, but in the context of the health trajectory that precedes and follows it—including ovarian aging, symptoms, metabolic change and long-term cardiovascular and brain health.

Cardiovascular + metabolic health

Understanding how reproductive history, pregnancy complications, PMOS, menopause and other women-specific factors interact with blood pressure, lipids, glucose, inflammation, body composition and long-term cardiovascular risk.

Autoimmune + inflammatory health

Exploring the relationships among immune function, reproductive health, hormonal transitions, pregnancy and chronic disease—and how those relationships may affect women's health over time.

Women's preventive care

Turning these insights into a new generation of preventive-care protocols that incorporate a woman's reproductive history, clinical history, current life stage and evolving risk—not simply her health today.

Building the research ecosystem for women's health

No single company, health system or dataset can answer these questions alone.

Tia partners with researchers, academic institutions, health systems, life sciences companies and health technology companies that bring different scientific capabilities, datasets and vantage points on women's lives.

Together, we can build a more complete picture of women's health—and turn that understanding into better care.

Participate in research

Tia patients may have opportunities to participate in research that advances our understanding of women's health and help shape better care over time. Participation in any research study is voluntary and does not affect access to or quality of care.

Learn about research participation

Build with us

We believe the next era of women's health research will be built collaboratively. We partner with researchers, academic institutions, health systems and technology partners bringing important questions and new ways of measuring women's health.

Collaborate with Tia